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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5b5e7ae309b95edbbc6834ab1c2e02a11b29b40888dbb63c398db26c79b9636f' 
  AND token = 'nZ3oF1Os+EkXGyaTmqAm3T2B02h9+Yy5sukq1f1tWts=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}