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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '309aef366ab30c6562281f10810b78482a0071c9b684324079564b33005bb246' 
  AND token = 'A+f7eLUXDiMxoHhV1y3f3bp6WHAGiC24ZdFoLybAfjA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}