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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8b597249ce74bfda182b44f644c52bac4c10a32ea59cbadb92b63997ab2815e2' 
  AND token = 'ZgFj0y2ZwGbKvCZQjUCMlvqp9/c8d2v/6b2hyENS/q4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}