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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8d9dfbcb2db144aaac2657e6e3aba56f9a496fa04622c6bc36d3964e7f28645f' 
  AND token = 'g8MK32IMCnAtS46uEq+Ebx7JFdJwvz3Igcc7t93L/AY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}