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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a3d200e1f5b34d87048a6bf73d39427baeeed5a7f5deadc7658d906c06ac301e' 
  AND token = 'u+kWWanIcKcNBSOSFw5ifP8gAkrrrXwz3EK8ygjpKMc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}