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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd4a3d4b534ee7b1fd4eda85a86cba9b2c6169f993c211ca668c3704e140be894' 
  AND token = 'cg7xbhkuUXexqGkFLHXBdSf+48FM2aD+myhk0bI9nj0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}