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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '43f875c396f1eda2588a2edcbe0c822878e203a6148276847d084163a14b8c03' 
  AND token = 'tc00pB/fBXjevVbj0GJ5IC4JrKaKkRo3mco6O6Dyzcw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}