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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d40675b268958184c5528a9e48a28037e984f2df4717b4b2221a115c1f43563' 
  AND token = 'meIeQrAmw+yH81VOR9b0IcVGYMUmONxKnXRV7h9dIqM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}