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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4f4b9781e60797eed6c93d6fd0669098300cf27da324ec17d594f125077a0a68' 
  AND token = 'LTND+ao5p/0HnFYlujn089LEV2kSNJdZxDu/WJ0eiUo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}