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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1846f6f7cf44adfa1551acb6c239fcd633967dee3d8d6ebc55adfd379e979e6f' 
  AND token = 'zsYPLMFRXhiNHlAy9zH50y4xt3ONURstIOOkTQ7EXAs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}