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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9b46bd3a633449c3fa6efae0364f360eefbbbf94fec1080906d7ece43c5d4f6d' 
  AND token = 'xs6Boh9ccqgnyUKc+MolOL53r/Rx8OSPFy+GH9aA0vI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}