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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '260731ad1cf1f319b8416e473678755431fb1f775f8f0a45f8a2e6fb5d0aadb1' 
  AND token = 'IXLRgVFQxREtlFL1IYfMIInsfKstN+IYQwobLh/7VVk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}