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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '21e290c780960ccb093c079a90dbfdf4fc1f264671e6e2a68cd3a10ba049b2e4' 
  AND token = 'Ib5D+JvLpH/eRNLEedvH3/HBCioE3D0Ml1wH9XpuEaY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00040

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}