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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fca9785e424269f1cb38f71dafb34cc3e12f292da6e7682de00a8f67ad840a63' 
  AND token = 'Wj5vjl7KyMyu0dCyJ+8KEQLLnKBevzAbKT9iRWhnTZM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}