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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '35978f848ca342da359d25ab84887444b379e14f90383a98adb866b10b23d301' 
  AND token = 'sQILnZH0xhiRFEL2yQKPGiC0d3Z0hqIshjChorVIPt0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}