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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '256c1cad37f0a7147ca9b1e43a8e2fdf7be8d6eef043425102a7194c87a9ae1d' 
  AND token = 'A3YaHAchm3q1Ko/bNH13a9TQmFb3RewASovMGsekZWc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}