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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '66636d2e375006ab63b0509f34af61516dd3a163b130da942da33e0f12594b35' 
  AND token = 'l5eMR9l3udpERrEduLybO2T+qNHIEQk6siXwQpiE6P0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}