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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ff6b43b94471a41f3e174d1c0620188cf75d81383998f5d8f50c44057acd9556' 
  AND token = 'l1kNJQGEDTsoloAw6a+set9Mt6bOOnxVGqcv0FlAJSE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}