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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b4862a90428d45d9958805bfc901e21166971e57a19a90fe2e7e7b868293c8b1' 
  AND token = 'ug5GnEP9y4or7OFSCHWRhX/yCN4sMgx01Snm7Ukm/DM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}