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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3e9a1e72fea749d8b258e567bb5bcbe3896fd5fc528efa7f467256772a00eec7' 
  AND token = '4V/RqdVwoPA3MkR+J9ZyQ/kyLxuQUZjJUckqmZ59pB8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}