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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '42af3a44d0392aef7deb493535b564ce1fd90d6a24a1ce3d570565ebe86fdac3' 
  AND token = 'SuTaAscamI017nCkj9uBp0RRcYDiN508mzGui0uN+Is=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}