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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e15c6c94ce327015b26581fdffb7a99053b706c9b54145b17fdb2e28ad7595af' 
  AND token = 'r9lLBg9Lu4Ucfda4HN3jKRCmMos8ArpxXkAVtnrx9Yw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}