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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '448edf8f156265329a1a9b388ff6f61256be511c0531362f9a523f4a4185a9ab' 
  AND token = 'wxM5/m9CFbjvMumlJkDP4C9dZPzQaYRMKe54p/sa+Ck=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}