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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3e6570cd2b68ee5ef0ee8e266af3e0cdde89c15bcdd8297445b80ff648437f31' 
  AND token = 'uG1m02IaFzIVTLoxQ0grMAKXIwYS3kOqb//xwT6hn2A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}