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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '44d8c3c801b0d7e60bc748793a5494403c04f02bd48bab749c36e2c675d6e90d' 
  AND token = 'd2z+B6yZISu12oYoRPdehXVR511rVWbMcuiA77ydccU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}