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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd58e3c669d87d4e12c224784c8b662b5f5f9531ee2f90022dc1a65226af4fc0f' 
  AND token = 'mbEan+LMylJCCTv6jpURtgJmyv7SAZEMUBosUu0uvFg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}