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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0b700f6a9fede1d3da7a714369fe5a2bbf0a287183835c141493dd120c3e6d3f' 
  AND token = 'VfTp+rZkXDTSEilT46bq9ite1LshETBDhyrFRi9zU4Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}