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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '51e352a22d8e304dfff3ccc0f2fc5fe4250cb85d3e8b05447d55220aaf98220c' 
  AND token = 'CoPRDfeTZ9y+oL9IFoc8zvTnzV359jsIE5LnpYKu6k4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}