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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '795e7c62d9c1267e3c8a3a2a9a3001596dba9648e1e9a562eeee311379a89019' 
  AND token = '3lHAMIPGNmTdN2yoPMZVjCPG9FFagPuRmHhpjXkltjM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}