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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4f9ca563321dbe3302830030059a439241c7c51fe6047a66b01926da98c00a04' 
  AND token = 'JRWurYbkdsPIM+8ZzGEc1UCpTWsCRFlVsJYfBnU3rwU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}