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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f99b8ab11f769003a697d4959c1ac3a35e4b18160cb8822f46d9c57f0818aba0' 
  AND token = 'ThDVSms0ivXcuqhNwxxau3L9CLAFMaBGRZsEoM34Ws0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}