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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3fd6f90d0129e39c03039a4437cab4410a942b2c3153b3bfbbec0f3a882c0e3e' 
  AND token = 'UHq0+RGZ6KTPlgEr4yWIh1Lcn3CLDOjR9TKRVXpBdqg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}