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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8d4df0b2f06d4a7b344ba2d09912f33d20b7f64f7101b0caa3163360d5c7ba52' 
  AND token = 'aIutmmtBBBZeYSrtePTf4s88cz4hRwkx/eGduzecyUY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}