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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '16b68ccb02b6e91520ec141ec0c74f8916b3baa3805f3ca4ce36f8e8517cdf86' 
  AND token = '7kq0qdQEOk3DQyMlJqGpxlNjLf0LHNmMBBcWyXdLdF8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}