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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a295a1f7ed2a3b6cdb75688cd440fd7d2d696649628f01814eb0c6d0adcdd581' 
  AND token = 'VCrVNt0mWIqP4vdMQfQSy1X9UIDk/3PcE/z/09fRcP8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}