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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80cdfc098eddb3e28f0243c8b0258b3158217794a5699bd4928c063c9421344a' 
  AND token = '4U74DF6g4v7BkWnvFPUVCoxknift58TVI5zylP/9VqM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}