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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5892b30e2cf4d2b4283e331c6638cdc0b15b69b241f0c45169dc9c2d4163c71d' 
  AND token = 'JEn85dfq9A3sb2JmQ57cs7kcCU5Ts8Ss/SS+C0Nz8nU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}