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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '79965e4f4d9c347431b543db6fe7b378779fd9380fa56c64f3cc9f0b5463057a' 
  AND token = 's2LcT1UcXar1M7AH/UnQD4P+UZi7mOTvU+4fbKAfPhU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}