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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3440f0d23988ae5f3a8a5c20d95eca30d0fdc5463326e6646da2fed9b11d2d26' 
  AND token = 'Ysty3cleeOUE0P791vvhxs+qIn72nrjhltwxlq3/NTI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}