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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72ef371fc1d1ba7c4b90727f74b8477380eb1909c9f39e352c53f83505154edb' 
  AND token = '2NG/BQHBgVV4So2m5BIUeA1t7A6tIrvadGhazXfkrhM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}