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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1b9eb512785db37d097dffefdd2589583edcab7626a273d020cba167fdff7cd0' 
  AND token = '04E+dU/2Upip0uwDn1U+ASE2bHi4uFvLgy/dR7ZpbV8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}