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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0d6bfd61ca1161bf530e33af50c5a3e36ef9360c7ffb3d8306eb86b78055d240' 
  AND token = '6Gc461sHSEciP8rrozn+QD+vqqJVpKE8EXM7r120Y00=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}