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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ece234028f378e775db9b560018927e00a3c04b6a1a03aa2c838e94107a50cdb' 
  AND token = 'Qk0qlsfw+Dra/PiVtuUL4z8OqpxgdxxuRp49ZEf0tDk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}