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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '37d5f5ec7e15a0f76133d444ed837ed4ea87f31708d6203318073d6ccfd453ee' 
  AND token = 'YaMYo4Pd8YNNw+osSxob/xcbwIS6Hx2DWxlcFEudBMM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}