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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4ecc9d032fc18e9633c7544c8985d833ab0cfa85b407d2419dc1087246fddbd1' 
  AND token = 'Bm+c2Qeld0CB2V6pT2Ml9PU3LVahYPdb5Atux8j1EmM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}