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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72416b84347d1a8e234848f00e5e7a1cde6fda469a33db74f4228efed487f216' 
  AND token = '+6SfdUJJVvxMDmOUaDju8C7c0SoD2GvOwbIJ8A7iH5c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}