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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2cf5c54be88adcefc6974450ed83d4eac8d3d62f0b98019845eb115dbde37c76' 
  AND token = '80utQ0pM83JwRrfw7KJz1sA2uompEKPtEuIk8eQ7sFo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}