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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2a046644108efb5a65e36d55029538312fd307f5b728ae3e1753c13bf1760b97' 
  AND token = 'RYdmxihA5fA/+oZqiPZL4XxVCsm+mQQR1X/ZDC/95fo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}