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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ad6ae727fda846c56ecf78f5fee942ffe2f5122732d3af89cab96a3f33c463a1' 
  AND token = 'lOfTAEtn3O/CMKNkdffnzbm5znmP988ERNivE3ZPBJ4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}