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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f11347209b4550d6e3d2d5ae1e4466a24c080db88a508e4b75b4c8e9be05ae51' 
  AND token = 'PTZZsFX23sYENLhVJbIlsAAWNevDT8bT2+F6np0wQu4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}